Model No.: ZP-29
2, since the tablet has a measurement accuracy, content uniformity, stable, easy to carry, transport, high degree of mechanization, large output, easy to take and so on, so the tablet is a modern pharmaceutical formulation of one of the most widely used forms. Production, including tablets, "said the material - granulated - tablet - coating - Packaging - boxing - storage" seven major steps. Tablet production line required pharmaceutical equipment together, so that a chain, will greatly enhance the efficiency of the production of tablets.
Tablets after mixing the drug with excipients uniformly pressed sheet preparation, the appearance of a circular and oval, triangular and other alien. Tablet production line is mainly based on customer yields and product properties, consistent production line design, production and the different nature of the product, provide different models and models. In tablet production line include: grinding and mixing, granulating, coating, tabletting and packaging equipment.
Because tablets have accurate measurement, content uniformity, stable, easy to carry, transport, high degree of mechanization, large output, easy to take and so on, so the tablet is a modern pharmaceutical formulation of one of the most widely used forms. Production, including tablets, "said the material - granulated - tablet - coating - Packaging - boxing - storage" seven major steps. Tablet production line required pharmaceutical equipment together, so that a chain, will greatly enhance the efficiency of the production of tablets.
Production of tablets in two ways: pressed powder and granules pellets; granules producer may generally be dry granulation; wet granulation; granulation step.
Powder producer is more suitable for hot, wet unstable drugs. Powder tabletting process is simple, less energy-efficient, step, but there are also powder flowability, compressibility is poor, easily lead lobes weaknesses.
At present, most of the particles using tablet method. Generally they include: shredders, sieving machines, mixers, granulators, dryers, tableting machines, coating machines.
1. wet granulation tabletting
Wet granulation tabletting method is a wet method were dried granules, after adding suitable auxiliary tabletting molding process. Where the drugs on the heat, humidity is relatively stable, generally use wet granulation tabletting method .
2. The dry granulation tabletting
Dry granulation tabletting method is a dry granulation of the particles by adding a suitable molding process after the dry materials tableting granulation tabletting method commonly used in heat-sensitive materials, water-labile drugs, simple, time saving time and labor. But there is a dry granulation which require special equipment to form the weight of large, severe dust, so as to increase opportunities for cross-contamination disadvantage.
3. Semi-dry granules compression method
Semi-dry granules compression method, also known as white granules compression method, the drug is mixed powder and pre-made good after tableting excipient particles forming process. This method is suitable for heat-sensitive and difficult to granulation, and poor formability drugs can also be used for fewer drug-containing granulated material.
First, the drug and excipients mixed. Containing a small amount of the drug or poison, tablet drama drugs should be used appropriate methods of drug dispersed uniformly.
Second, Where volatile or light and heat labile drugs in the production process should be sunscreen, avoid heat, to avoid component damage or failure.
Third, the material or granules before tableting water should be controlled in order to meet the needs of production process, the tablets during storage to prevent mildew, deterioration.
Fourth, lozenges, oral patch, chewable tablets, dispersible tablets, effervescent tablets, etc. may be added as needed, flavoring agents, coloring agents and additional flavoring agents.
Fifth, to increase stability, mask the bad odor of drugs, improve the appearance of the tablets, etc., can be coated tablets. Sixth, the complete tablet should look smooth, uniform color, have a suitable hardness and wear resistance, except as otherwise provided, for non-coated tablets, tablets should meet the requirements friability test method to prevent packaging, transport process the worn or broken. Seven, the tablet dissolution, release, content uniformity, microbial limits shall comply with the requirements. If necessary, the film-coated tablets should check the residual solvent.
Eight, except as otherwise provided, the tablets should be sealed.
From the late 19th century, the tablet has been widely used and has been well received, to the late 19th century with the advent of tablet devices and continuous improvement, production and application of the tablet has been rapid development. Over the last decade, tablet production technology and machinery and equipment also have a larger development, such as boiling granulation, direct compression tablets whole, semi-film coatings, new materials, new technology and so on. In short, the tablet has become one of the varieties, yield, versatile, easy to use and storage, quality and stability, a tablet formulation in the total amount of Chinese Pharmacopoeia and many other countries that were contained in, account 1/3, showing the breadth of application.
|Max. tablet dia.||18mm||18mm||18mm|
|Max. filling depth||15||15||15|
|Max. tablet thickness||6||6||6|
Product Categories : Tablet Press Machine
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